Strong In Vivo Activation of NF- B in Mouse Lenses by Classic Stressors

نویسندگان

  • George Alexander
  • Harald Carlsen
  • Rune Blomhoff
چکیده

METHODS. Transgenic mice containing the NFB-luciferase reporter were injected with LPS, TNFor, exposed to UV-B. After various exposure times, the mice were killed, and ocular, liver, lung, kidney, spleen, and skin tissue were obtained. Tissue homogenates were examined for luciferase activity with a luminometer. Groups of mice were also imaged in vivo through a light-intensified camera system to assess NFB activity.

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تاریخ انتشار 2003